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Scientific awareness on Stem Cell Banking

Temjenkaba

Life Cell is India’s first and largest stem cell bank which was Established in 2004, and is India’s first and largest stem cell bank enjoying the trust of 1,00,000 parents who have banked their children’s stem cells with the company. With state­of­the­art laboratories at Chennai & Gurgaon and a network spread over 100n service centres in the country & footprints in GCC countries, Life Cell is also the most recommended stem cell bank by gynaecologists.

The company is also the most accredited stem cell bank with certifications from national and international organization, this was stated by Brig.(Dr) Paramjit Singh while addressing at Workshop on scientific awareness stem cell banking held at Hotel ACACIA at Diampur on 11th of February 2015th with resources person Brig.(DR) Paramjit Singh DHOT from Life cell international PVT Ltd Gurgaon to create awareness on the stem cell banking from which people can benefit by way of treatment of more than 80 medical conditions which was attended by senior doctors from Kohima and Diampur.

Brig. (Dr. Paramjitsingh DHO inform that Life Cell is also the only player in the industry providing comprehensive stem cell solutions including menstrual stem cell banking, R&D and point­of­care stem cell therapy for orthopaedic, vascular and cardiovascular specialties He added that Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells and are the best described in the context of normal human development. Human development begins when a sperm fertilizes an egg and creates a single cell that has the potential to form an entire organism and this fertilized is tot potent, meaning that its potential is total.

In the first hours after fertilization, this cell divides into identical tot potent cells which means that either one of these cells, if placed into a woman’s uterus, has the potential to develop into a foetus.  Paramjit Singh mentioned that Cells capable of giving rise to most tissues of an organism are called pluripotent and comprise the inner cell mass cells in an embryo. The pluripotent cells undergo further specialization into stem cells that are committed to give rise to cells that have a particular function.

The examples of stem cells include blood stem cells which give rise to red blood cells, white blood cells & platelets; skin stem cells which give rise too various types of skin cells; and these more specialized stem cells are called multi potent. The advantage of Cord Blood stem cells are that it is easily available; it is non­invasive collection procedure which is better tolerated across the HLA barrier and has a lower frequency of CMV infection.

As per information it is worth mentioning that Over 30.000 cord cell blood transplants have so far done globally and Clinical phase 111 trials are on­going for a number of diseases which will soon result into stem cell therapy in the clinics. Life cell international, first and most accredited private cord blood bank has over hundred collection centre in India and aboard stores over 1,27,000 cord blood units at –degree centigrade in liquid nitrogen with of life of 23.5years. It is the only cord blood bank in the world with a dual storage facility at Chennai and Manesar.

The first transplantation of Umbilical Cord Blood was successfully performed in October 1988 by Gluck man et al to treat a boy with Fanconi’s anaemia and he is alive, well and completely cured of the haematological and life threatening manifestation of his disease more than 25 years after the procedure.

The donor, the Gluck man et al was his new born sister was a perfect HLA match for her brother. The medical fraternity are excited by the current state of knowledge and the immense potential in the exponential development in this field. The major limitations of using HLA­ matched related sibling donors in HSCT emphasize on the facts that only 30% to 40% of recipients have a HLA­ matched related family donor hence the search for an alternative source of HSC.

New born Screening (NBS) is a simple test taken at birth to enable early detection of condition in babies. The conditions screened for are individually rare but collectively more common. ­1 in 300 are diagnosed in US based on population screening for 29 conditions. The purpose of new born screening is to enable early detection of pre­symptomatic babies, to enable early treatment, to improve health, to reduce anxiety caused by uncertainty over symptoms before clinical diagnosis is made.

NBS is a public health success story. It is mandated by almost all developed countries as it saves lives, prevents disability, and in fact saves money. The widespread implementation of NBS in the US led it to its recognition as the ‘Ten Great Public Health Achievements’ in the US, between 2001 – 2010 (CDC, May 2011). In the Philippines, the New­born Screening Act of 2004, Article 1 Section 3, states that “every new-born must be given access to new­born screening”.

Temjenkaba is based in Nagaland